
Mississippi Cannabis Laws & Dispensary Compliance Guide
Last reviewed: June 14, 2026

Dutchie does not provide compliance advice. Merchants are responsible for their own compliance. External Dutchie compliance documentation may be updated from time to time and has been prepared for informational purposes only, is not intended to provide, and should not be relied on for, tax, legal or compliance advice. Merchants should consult their own tax, legal and compliance advisors to determine how best to operate within the cannabis industry.
Market Type
In Mississippi, cannabis is regulated by multiple agencies. The Mississippi Department of Health, through the Mississippi Medical Cannabis Program (MMCP), regulates most of the industry, while dispensaries are overseen by the Department of Revenue. The Mississippi Board of Pharmacy operates the Prescription Monitoring Program (PMP).
Tracking & Inventory
Mississippi uses a combination of Metrc and the PMP. Sales are recorded in Metrc, which also tracks inventory and provides the patient allotment lookup. The PMP is a patient-lookup and dispensing-reporting system operated by the Board of Pharmacy; it is not the system of record for sales transactions.
Purchase Limits
Medical
- A cardholder may not receive more than 24 MMCEUs in a rolling 30 days.
- Non-resident cardholders may obtain 12 MMCEUs per 15-day period (two 15-day periods per year).
Metrc tracks the monthly allotment values. A Metrc allotment check must be performed before dispensation.
Equivalencies
Mississippi uses Mississippi Medical Cannabis Equivalency Units (MMCEUs) to define limits and equivalence. One (1) MMCEU is equal to:
- Three and one-half (3.5) grams of medical cannabis flower;
or - One (1) gram of total THC in a cannabis concentrate (per SB 2748);
or - One (1) gram (1,000 mg) of total THC in an infused product.
Taxes
Medical
Standard retail sales taxes apply to cannabis sales.
Additionally, a 5% excise tax applies only to cannabis flower or trim at a cultivation facility’s first sale or transfer to a medical cannabis establishment. It does not apply at retail.
Delivery
State Resources
Cannabis waste disposal license type
There is a cannabis waste disposal license. Stores and other licensees will not be allowed to waste their own product, and instead must transfer to an appropriately permissioned license for destruction.
